C-reactive protein gene variants: independent association with late-life depression and circulating protein levels
نویسندگان
چکیده
منابع مشابه
Association of polymorphisms in the CRP gene with circulating C-reactive protein levels and cardiovascular events.
CONTEXT C-reactive protein (CRP) is an inflammation protein that may play a role in the pathogenesis of cardiovascular disease (CVD). OBJECTIVE To assess whether polymorphisms in the CRP gene are associated with plasma CRP, carotid intima-media thickness (CIMT), and CVD events. DESIGN, SETTING, AND PARTICIPANTS In the prospective, population-based Cardiovascular Health Study, 4 tag single-n...
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The allele and haplotype frequency of the -1654 C/T and -1641 A/G protein C (PC) gene promoter polymorphisms was determined and analyzed according to circulating PC concentrations in 394 healthy subjects aged 20 to 60 years. The CG haplotype was associated with a lower PC concentration in both homozygous and heterozygous subjects compared with noncarriers. The TA allele had the reverse effect, ...
متن کاملAssociation between Depression and C-Reactive Protein
Objective. Depression has been associated with increased cardiovascular disease risk, and a depression-related elevation of high sensitivity C-reactive protein (hs-CRP) has been proposed as a possible mechanism. The objective of this paper is to examine association between depression and high sensitivity C-reactive protein (hs-CRP). Methods. Subjects consisted of 508 healthy adults (mean age 48...
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Although periodontitis is a chronic inflammatory disease but some factors of acute inflammation phase are involved in this disease among which is the C-Reactive protein (CRP). To minimize its effects, anti-inflammatory drugs or non-pharmacological approaches such as oral hygiene is recommended. CRP can also be used for the prediction and early detection of periodontal disease. The aim of the pr...
متن کاملSerum Adenosine Deaminase Activity and C-Reactive Protein Levels in Patients with Brucellosis
Background and Objective: Brucellosis is a main transmittable zoonotic disease, which is endemic, and a common health burden in Iran. Adenosine deaminase (ADA) is an essential enzyme which is involved in purine metabolism and its role in immune system is very important. The aim of this study was to determine serum changes of ADA and C-reactive protein (CRP) levels in patients with brucellosi...
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ژورنال
عنوان ژورنال: Translational Psychiatry
سال: 2015
ISSN: 2158-3188
DOI: 10.1038/tp.2014.145